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Boulting Laboratory

Selected Publications

Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability.

Boulting GL*, Durresi E*, Ataman B*, Sherman MA*, Mei K, Harmin DA, Carter AC, Hochbaum DR, Granger AJ, Engreitz JM, Hrvatin S, Blanchard MR, Yang MG, Griffith EC, Greenberg ME

Nature Neuroscience  2021  https://doi.org/10.1038/s41593-020-00786-1

Evolution of Osteocrin as an activity-regulated factor in the primate brain.

Ataman B*, Boulting GL*, Harmin DA, Yang MG, Baker-Salisbury M, Yap EL, Malik AN, Mei K, Rubin AA, Spiegel I, Durresi E, Sharma N, Hu LS, Pletikos M, Griffith EC, Partlow JN, Stevens CR, Adli M, Chahrour M, Sestan N, Walsh CA, Berezovskii VK, Livingstone MS, Greenberg ME.

Nature  2016  https://doi.org/10.1038/nature20111

Pathways Disrupted in Human ALS 
Motor Neurons Identified 
through Genetic Correction of Mutant SOD1.

Kiskinis E*, Sandoe J*, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, Ichida J, Di Costanzo S, Atwater N, Maeder ML, Goodwin MJ, Nemesh J, Handsaker RE, Paull D, Noggle S, McCarroll SA, Joung JK, Woolf CJ, Brown RH, Eggan K.

Cell Stem Cell  2014   http://dx.doi.org/10.1016/j.stem.2014.03.004

A functionally characterized test set of human induced pluripotent stem cells.

Boulting GL*, Kiskinis E*, Croft GF*, Amoroso MW*, Oakley DH*, Wainger BJ, Williams DJ, Kahler DJ, Yamaki M, Davidow L, Rodolfa CT, Dimos JT, Mikkilineni S, Macdermott AB, Woolf CJ, Henderson CE, Wichterle H, Eggan K.

Nature Biotechnology 2011  http://dx.doi.org/10.1038/nbt.1783

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.

Di Giorgio FP, Boulting GL, Bobrowicz S, Eggan KC.

Nature Biotechnology 2008   http://www.sciencedirect.com/science/article/pii/S1934590908005225